Titrate the dosage of acetaminophen and codeine phosphate tablets slowly and gradually in geriatric patients and often reevaluate the individual for indications of central anxious procedure despair (see WARNINGS).
Emphasize to sufferers and their caregivers the value of studying the Medication Information that they'll receive from their pharmacist anytime an opioid analgesic is dispensed to them.
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Take this medication by mouth as directed by your health care provider. Chances are you'll just take this drug with or without the need of food items. For those who have nausea, it may assistance to consider this drug with food.
Though serious, lifestyle-threatening, or deadly respiratory melancholy can take place Anytime for the duration of using acetaminophen and codeine phosphate tablets, the chance is finest in the initiation of therapy or following a dosage improve.
Just after stopping use of a CYP2D6 inhibitor, take into account lessening the acetaminophen and codeine phosphate tablets and Appraise the affected individual for indicators and indicators of respiratory depression or sedation.
If concomitant use with CYP2D6 inhibitors is important, assess the patient for lessened efficacy or signals and indications of opioid withdrawal and look at rising the acetaminophen and codeine phosphate website tablets as necessary.
Reserve concomitant prescribing of acetaminophen and codeine phosphate tablets and benzodiazepines or other CNS depressants to be used in people for whom alternate procedure website solutions are insufficient (see Safety measures, Drug Interactions).
When there won't be any regular opioid tapering schedules suitable for all more info patients, excellent clinical apply dictates tapering in tiny increments website (e.
Advise the two people and caregivers in regards to get more info the threats of respiratory melancholy and sedation when acetaminophen and codeine phosphate tablets are made use of with benzodiazepines or other CNS depressants (which includes Alcoholic beverages and illicit medication). Suggest sufferers never to drive or work heavy machinery right until the effects of concomitant use with the benzodiazepine or other CNS depressant happen to be decided.
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Watch this sort of people for signs of sedation and respiratory melancholy, especially when initiating therapy with acetaminophen and codeine phosphate tablets.
Usage of opioids for an extended time frame could result in decreased fertility in females and males of reproductive potential. It is not recognized whether or not these effects on fertility are reversible (see ADVERSE REACTIONS).
Read the Medication Information furnished by your pharmacist before you start getting acetaminophen/codeine and every time you receive a refill. In case you have any thoughts, inquire your medical doctor or pharmacist.